Phytochemistry and Biological Activity Perspectives of Rheum
Species
Author(s):
Pramod Singh, Geeta Joshi nee Pant and MSM
Rawat Pages 84 - 93 ( 10 )
Abstract:
The genus Rheum is a member of the family
Polygonaceae. Rheum species, generally known as Rhubarb growing in high
altitude, are important medicinal herbs containing secondary metabolites and
grow in India, China, Korea, and Japan. Several chemical constituents from
Rheum species are pharmacologically important. Besides being used as herbal
medicine and also used in the vegetables and for making natural dyes. More than
250 constituents including anthraquinones (emodin, chrysophanol, physcion,
aloe-emodin, and emodin glycosides), anthrones, flavonoids, acylglucosides,
pyrones stilbene etc. are the major bioactives of rhubarb that exhibit several
biological activities are used folk medicine for the treatment of fever,
dysentery, blood coagulation, laxative, anticancer and also used in various
skin diseases. This article is an attempt to highlight several of chemical
constituents isolated from these species and their medicinal properties.
Keywords:
Rhubarb, anthraquinones, chemical
constituents, biological activities, polygonaceae, emodin.
Affiliation:
Department of Chemistry, H. N. B. Garhwal
University, (A Central University) Srinagar Garhwal, Uttarakhand,
India-246174., Doon University, Dehradun, Uttarakhand, India-248 001.
Graphical Abstract:
Saikosaponin B3, a triterpene glycoside, is a saikosaponin isolated from Bupleurum chinese DC. Bupleurum chinese DC, also called as Bupleuri Radix, is one of the most important crude drugs used inmany traditional Chinesemedicines. And it is believed that saikosaponins are responsible for part of the pharmaceutical properties of Bupleuri Radix. Saikosaponin B3
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