Thursday, December 29, 2016
Thursday, December 22, 2016
Thursday, December 15, 2016
Monday, December 12, 2016
Friday, December 9, 2016
Friday, December 2, 2016
Thursday, November 24, 2016
Monday, November 21, 2016
Thursday, November 10, 2016
Call For Paper
Bentham Science Publishers would like to invite you to submit your research paper for publishing in the Journal of
The Natural Products Journal
Friday, November 4, 2016
Highlighted Article: Adequacy of Quality Assurance Programs for a Corn Meal Production Unit
Adequacy of Quality Assurance Programs for a Corn Meal Production Unit
Author(s):
Eliane Maria Ravasi Stéfano Simionato, Jéssica Januário Cardoso, Mayara Cristina Gonçalves, Tânia Regina Kovalskia, Érica Regina Daiuto, Rogério Lopes Vieites and Robert E. Smith Pages 27 - 32 ( 6 )
Abstract:
To ensure the quality, the processing of artisanal corn meal in a production unit located in the southeastern state of São Paulo was evaluated. It handles an average of 15 tons/months, all under GMP and HACCP regulations. Of the 153 items examined on a checklist, only 42 were in compliance. In addition, the following Control Points (CPs) were identified: humidification of hominy and corn. The Critical Control Points (CCPs) were: the water, the oven, the screen that covered the humidification tank and final product. Some steps were not GMP-compliant, so corrective measures based on the CP and CCPs were suggested. One important factor was the need to comply with the specific legislation about folic acid and iron supplementation in the product. Another was the technique used to add them to the product.
Keywords:
Food security, good manufacturing practices, HACCP, Zea mays L.
Affiliation:
Park University, 8700 River Park Drive, Parkville, MO 64152 USA
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For More Information Please Visit Our Website The Natural Products
Thursday, October 27, 2016
Most Accessed Article: Phytochemistry and Biological Activity Perspectives of Rheum Species
Phytochemistry and Biological Activity Perspectives of Rheum
Species
Author(s):
Pramod Singh, Geeta Joshi nee Pant and MSM
Rawat Pages 84 - 93 ( 10 )
Abstract:
The genus Rheum is a member of the family
Polygonaceae. Rheum species, generally known as Rhubarb growing in high
altitude, are important medicinal herbs containing secondary metabolites and
grow in India, China, Korea, and Japan. Several chemical constituents from
Rheum species are pharmacologically important. Besides being used as herbal
medicine and also used in the vegetables and for making natural dyes. More than
250 constituents including anthraquinones (emodin, chrysophanol, physcion,
aloe-emodin, and emodin glycosides), anthrones, flavonoids, acylglucosides,
pyrones stilbene etc. are the major bioactives of rhubarb that exhibit several
biological activities are used folk medicine for the treatment of fever,
dysentery, blood coagulation, laxative, anticancer and also used in various
skin diseases. This article is an attempt to highlight several of chemical
constituents isolated from these species and their medicinal properties.
Keywords:
Rhubarb, anthraquinones, chemical
constituents, biological activities, polygonaceae, emodin.
Affiliation:
Department of Chemistry, H. N. B. Garhwal
University, (A Central University) Srinagar Garhwal, Uttarakhand,
India-246174., Doon University, Dehradun, Uttarakhand, India-248 001.
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Friday, October 21, 2016
Friday, October 7, 2016
Recently Published Issue of the Journal The Natural Products Journal
The Natural Products Journal a peer reviewed journal aims to publish all the latest and outstanding developments in natural products. The Natural Products Journal publishes original research articles, reviews, letters and guest edited issues on all aspects of research and development in the field including: isolation, purification, structure elucidation, synthesis and bioactivity of chemical compounds found in nature.
Following are the articles from the journal The Natural Products Journal, 5 Issue 2:
Article: Secondary Metabolites Derived from Actinomycetes: Iron Modulation and Their Therapeutic Potential
Author(s): Anil K. Sharma, Vikas Beniwal, Raman Kumar, Kamia Thakur and Rohit Sharma
Article: HPTLC Assisted Evaluation of Picroside Content in the Accessions of Picrorhiza kurrooa Grown at Different Altitudes in Nepal
Author(s): J.N. Sah, V.K. Varshney and I.C. Dutta
Article: Chemical Constituents and Biological Activities of Genus “Skimmia”
Author(s): Manjul Gondwal, Geeta Joshi Nee Pant, Bhanu Pratap Singh Gautam and Monika Gondval
Article: Sensorial Characteristics of a Diet and Conventional Fig Compote
Author(s): Priscilla Karim Caetano, Erica Regina Daiuto, Rogerio Lopes Vieites, Aline de Oliveira Garcia and Robert E. Smith
Article: Extraction and Characterization of Moringo olifera Gum as Pharmaceutical Suspending Agent
Author(s): Sumedha Pant, Rishabha Malviya and Pramod Kumar Sharma
Article: Sauropus androgynus Leaves for Health Benefits: Hype and the Science
Author(s): Hock Eng Khoo, Azrina Azlan and Amin Ismaila
Article: Grafting Technique with Special Emphasis on Natural Gums: Applications and Perspectives in Drug Delivery
Author(s): Rohit R. Bhosale, H.V. Gangadharappa, Afrasim Moin, D.V. Gowda and Riyaz Ali M. Osmani
For details, please visit: http://bit.ly/1K3c6P9
courtesy by Bentham Insight
Friday, September 30, 2016
Friday, September 2, 2016
Chemical Constituents and Biological Activities of Simira Genus: A Contribution to the Chemotaxonomic of Rubiaceae Family
Author(s):
Vinicius F. Moreira, Ivo J. C. Vieira and Raimundo Braz-FilhoPages 290-298 (9)
Abstract:
The Simira genus belongs to the Rubiaceae family. Studies of this genus have attracted interest, mainly due to phototoxic activities, antifebrile, tonic and purgative presented by some secondary metabolites isolated from drug value of species of this genus. This study is a review of the Simira genus, through the acquisition of data from studies of phytochemicals and evaluation of biological activities of the species that compose it, in order to contribute their chemotaxonomic classification within the family.
Keywords:
Biological activities, chemical constituents, chemotaxom, phytochemicals, Rubiaceae, Simira.
Affiliation:
Sector of Natural Products Chemistry, Universidade Estadual do Norte Fluminense Darcy Ribeiro, 28013-602 Campos dos Goytacazes-RJ, Brazil.
Graphical Abstract:
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Effects of Agaricus Blazei Extract Plus Lactoferrin or Lactoferrin Alone on Tumor Growth and UFT-Induced Adverse Reactions in Sarcoma 180- or Highly Metastatic Osteosarcoma LM8-Bearing Mice
Author(s):
Yoshiyuki Kimura, Maho Sumiyoshi and Kou-ichi UsukiPages 57-69 (13)
Abstract:
Objective: The protective effects of Agaricus blazei extract (ABE) and lactoferrin (LF) on 5-FU derivative-induced adverse reactions remain unclear. We examined the effects of a combination of ABE and LF on tumor growth and metastasis, as well as UFT-induced adverse reactions using a highly metastatic model in osteosarcoma LM8-bearing mice.
Methods: In this study, we examined the antitumor activity and adverse reactions, such as myelotoxicity and body-weight loss, of the cancer chemotherapy drug a 5-FU derivative, UFT (50 mg/kg) when given with ABE (9:1, w/w; 0.43 or 1.4 g/kg, twice daily) and LF (100 or 300 mg/kg, twice daily) in sarcoma 180- or osteosarcoma LM8-bearing mice.
Key Findings: ABE-LF or LF inhibited tumor growth and metastasis to the lung without causing adverse reactions in LM8-bearing mice. ABE-LF or LF prevented the reductions induced in the number of red blood cells, leukocytes, and platelets, as well as hemoglobin levels and the hematocrit percentage by UFT without affecting the antitumor and antimetastatic effects of UFT. Since neither ABE nor LF inhibited the phosphorylation of 5-FU, the protective effects of ABE-LF or LF on UFT-induced myelotoxicity (reductions in red blood cell numbers) could not be attributed to the inhibition of 5-FU phosphorylation.
Conclusion: These results suggest that the protective effects of LF and/or ABE-LF on the adverse events induced by UFT toxicity such as myelotoxicity may be partly due to the myelopoietic actions of LF.
Keywords:
Adverse reaction, Agaricus blazei extract, Myelotoxicity, Lactoferrin, UFT (tegafur/uracil).
Affiliation:
Division of Biochemical Pharmacology, Department of Basic Medical Research, Ehime University Graduate School of Medicine, Toon City, Ehime 791-0295, Japan.
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An Acetylated Triterpene Glycoside and Lignans from Phyllanthus myrtifolius and their Antibacterial Activities
Author(s):
Neneng Windayani, Lia D. Juliawaty, Euis H. Hakim, Komar Ruslan and Yana M. SyahPages 152-157 (6)
Abstract:
Phytochemical investigation on the methanol extract of Phyllanthus myrtifolius leaves led to the isolation of a new oleanan derivative, 3β-(3’,4’-di-O-acetyl-α-L-arabinopyranosyl)-12-oleanen- 28-oic acid (1). The structure of compound 1 was determined mainly by extensive NMR data analysis. Together with this compound, six arylnaphtalene lignans 2–7 were also isolated and identified. The isolated compounds 1–7 were tested for their antibacterial activities against eight pathogenic bacteria, showing that compound 1 exhibited highest activity.
Keywords:
Antibacterial, euphorbiaceae, lignans, oleanane, Phyllanthus myrtifolius, triterpene.
Affiliation:
Natural Products Chemistry Research Group, Organic Chemistry Division, Institut Teknologi Bandung, Jalan Ganesha 10, Bandung 40132, Indonesia.
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Effects of Eleutherococcus senticosus Cortex on Recovery from the Forced Swimming Test and Fatty Acid β-Oxidation in the Liver and Skeletal Muscle of mice
Author(s):
Maho Sumiyoshi and Yoshiyuki KimuraPages 49-55 (7)
Abstract:
Objective: The root and stem barks of Eleutherococcus senticosus have been used to treat emotional and physical fatigue in China, Russia, Korea, and Japan. The effects of E. senticosus on recovery from physical fatigue and the expenditure of energy currently remain unclear. We herein examined the effects of E. senticosus extract on recovery from physical fatigue after the forced swimming test as well as fatty acid β-oxidation in the liver and skeletal muscle of mice.
Methods: 1) Physical fatigue; E. senticosus extract (500 and 1000 mg/kg, twice daily) was administered orally to ICR male mice for 7 consecutive days. After swimming had been performed for 15 min, each mouse was placed on the cover of a 100-mm culture plate, and the time for each mouse to move away from the cover was measured. 2) Fatty acid β-oxidation in the liver and skeletal muscle; E. senticosus extract (500 and 1000 mg/kg) was administered orally twice daily to C57BL/6J male mice for 21 consecutive days. The initial and final body and liver weight were measured, and then fatty acid β-oxidation activity in the liver and skeletal muscle was measured by methods using [1-14C] palmitic acid.
Key Findings: Recovery times after forced swimming were shorter in E. senticosus extract (500 and 1000 mg/kg)-treated mice than in vehicle-treated mice. The body and liver weight had no effect by the oral administration of E. senticosus extract, vitamin mixture and L-carnitine. Fatty acid β-oxidation activity in skeletal muscle was increased by E. senticosus extract (500 and 1000 mg/kg).
Conclusion: E. senticosus may enhance recovery from physical fatigue induced by forced swimming by accelerating energy changes through fatty acid β-oxidation in skeletal muscle.
Keywords:
Anti-fatigue, Eleutherococcus senticosus, Fatty acid β-oxidation in the liver and skeletal muscle, Forced swimming.
Affiliation:
Division of Biochemical Pharmacology, Department of Basic Medical Research, Ehime University Graduate School of Medicine, Toon City, Ehime 791-0295, Japan
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