An Acetylated Triterpene Glycoside and Lignans from Phyllanthus myrtifolius and their Antibacterial Activities

Author(s):

Neneng Windayani, Lia D. Juliawaty, Euis H. Hakim, Komar Ruslan and Yana M. SyahPages 152-157 (6)

Abstract:

Phytochemical investigation on the methanol extract of Phyllanthus myrtifolius leaves led to the isolation of a new oleanan derivative, 3β-(3’,4’-di-O-acetyl-α-L-arabinopyranosyl)-12-oleanen- 28-oic acid (1). The structure of compound 1 was determined mainly by extensive NMR data analysis. Together with this compound, six arylnaphtalene lignans 2–7 were also isolated and identified. The isolated compounds 1–7 were tested for their antibacterial activities against eight pathogenic bacteria, showing that compound 1 exhibited highest activity.

Keywords:

Antibacterial, euphorbiaceae, lignans, oleanane, Phyllanthus myrtifolius, triterpene.

Affiliation:

Natural Products Chemistry Research Group, Organic Chemistry Division, Institut Teknologi Bandung, Jalan Ganesha 10, Bandung 40132, Indonesia.

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